University of Wisconsin–Madison

Congratulations to Ray Zhang (MD PhD Student, Kuo lab) First author of new Nature Review!

RayZhangBeyond the margins: real-time detection of cancer using targeted fluorophores

Ray R. Zhang, Alexandra B. Schroeder, Joseph J. Grudzinski, Eben L. Rosenthal, Jason M. Warram, Anatoly N. Pinchuk, Kevin W. Eliceiri, John S. Kuo & Jamey P. Weichert

Published online: 17 January 2017 | doi:10.1038/nrclinonc.2016.212

Intraoperative fluorescence enables highly specific real-time detection of tumours at the time of surgery. In particular, near-infrared (NIR) fluorescence is a promising tool currently being tested in clinical settings. Zhang et al. discuss the latest developments in NIR fluorophores, cancer-targeting strategies, and detection instrumentation for intraoperative cancer detection, as well as the challenges associated with their effective application in clinical settings.